FIGURE 4.

Clinical assessment of gait cycle aberrations in small rodents across the median lifespan in percent (data replotted from Altun et al., 2007 and unpublished data). The different gait cycles phases and the coordination between limbs are preserved (index = 0) until the final 20% of the life-span when these functions progressively deteriorate. However, note that there is a large variance among individual rats in the progression of this aging-induced impairment and that some very old rats still have an intact gait cycle.