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. 2021 Jul 2;12:681646. doi: 10.3389/fendo.2021.681646

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Copyright © 2021 Wong, He, Sze, Huang, Ko, Bian and Wong

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Histological distribution of SPX expression in the pituitary. (A) Immunoreactivity of SPX detected by anti-SPX in the mouse pituitary covering the areas of pars nervosa, pars intermedia and pars distalis. (B) SPX expression in the pars nervosa and pars intermedia. SPX signals were located in pituitary cells forming the matrix of pars nervosa and pars intermedia. (C) SPX expression in the pars distalis. SPX immunostaining was observed in cell clusters located in the outer edge of the pars distalis. In this study, parallel staining with NRS was used as the negative control and the numbers on the side (×25, ×100, ×200, and ×400) represent the magnification of the respective pictures.