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The SGC7901/DDP cell line exhibited multidrug resistance to DDP, DOX, and 5-fluorouracil (5-FU).
| Cell line | IC50 of DDP (μM) | IC50 of DOX (μM) | IC50 of 5-FU (μM) |
|---|---|---|---|
| SGC7901 | 0.714 | 1.074 | 6.139 |
| SGC7901/DDP | 1.319 | 1.612 | 292.8 |
| Resistance index | 1.86 | 1.501 | 47.70 |
Resistance index (RI) = IC50 (SGC7901/DDP)/IC50 (SGC7901). The RIs of DDP, DOX, and 5-fluorouracil (5-FU) were 1.86, 1.50, and 47.70, respectively (Table 1). Resistance index of BBD on SGC7901/DDP cells.
