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BBD reversed MDR in SGC-7901/DDP cells.
| Chemotherapy drugs | IC50 of DDP (μM) | IC50 of DOX (μM) | IC50 of 5-FU (μM) |
|---|---|---|---|
| BBD (0 mg/mL) | 0.251 | 1.329 | 85.264 |
| BBD (0.5 mg/mL) | 0.162 | 0.284 | 23.952 |
| Reversal fold (RF) | 1.549 | 4.680 | 3.560 |
Reversal fold (RF) = alone chemotherapy IC50/combination chemotherapy. The ability of BBD to reverse the resistance of SGC-7901/DDP cells to several chemotherapeutic drugs is shown in Table 2. Reverse effect of BBD on SGC7901/DDP cells.
