Skip to main content
. 2021 Jul 12;13:5573–5585. doi: 10.2147/CMAR.S307595

Figure 1.

Figure 1

CircHIPK3 expression was increased in PTX-resistant BC tissues and cells. Relative expression of circHIPK3 by qRT-PCR in 38 pairs of BC tissues and adjacent normal breast tissues (A), BC tissues from 13 primary patients (PTX-sensitive tissues) and 25 recurrent patients (PTX-resistant tissues) after treatment based on PTX chemotherapy (B), MCF-10A, MDA-MB-231, MCF-7, MDA-MB-231/PTX and MCF-7/PTX cell lines (C). (D and E) RNase R assays in MDA-MB-231/PTX and MCF-7/PTX cells. (F and G) Subcellular localization assays in MDA-MB-231/PTX and MCF-7/PTX cells. ***P < 0.001 by the Mann–Whitney U-test, Student’s t-test or ANOVA with Tukey’s post hoc test.