Table 3.
Duration of diagnosed diabetes |
Intracranial atherosclerotic stenosis, n (%) |
Unweighted model |
Weighted model |
|||||||
---|---|---|---|---|---|---|---|---|---|---|
n | none | stenosis <50% | stenosis ≥50% | OR | (95%CI) | p-value | OR | (95%CI) | p-value | |
Never (no diabetes) | 1135 | 787 (69.3) | 241 (21.2) | 107 (9.4) | 1 (ref) | - | - | 1 (ref) | - | - |
Less than 10 years | 345 | 253 (73.3) | 64 (18.6) | 28 (8.1) | 0.88 | (0.67, 1.16) | 0.37 | 0.87 | (0.62, 1.23) | 0.42 |
10 to 19 years | 113 | 73 (64.6) | 26 (23.0) | 14 (12.4) | 1.32 | (0.87, 2.01) | 0.19 | 1.35 | (0.82, 2.20) | 0.23 |
20years or longer | 51 | 25 (49.0) | 15 (29.4) | 11 (21.6) | 2.52 | (1.45, 4.39) | <0.01 | 2.04 | (0.90, 4.62) | 0.09 |
Total, n | 1644 | 1138 | 346 | 160 | P-value for trend=0.02 | P-value for trend=0.13 |
Odds ratios (ORs) were adjusted for age, sex, race-left (five categories), education, medications for hypertension and cholesterol (yes/no), systolic blood pressure (mmHg), non-HDL-cholesterol (mg/dL), and smoking (current/non-current). Those adjusting covariates were the ones assessed at Visit 5.