Table 2.
Changing diagnostic work-up for celiac disease in children in the Netherlands
| Characteristics | 1975–1990 % (n=223) |
1993–2000 % (n=1017) |
2010–2013 % (n=898) |
P value |
|---|---|---|---|---|
| Chronic diarrhoea | 72 | 41 | 25 | <0.01 |
| Abdominal distension | 76 | 48 | 28 | <0.01 |
| Growth failure in height and weight | 63 | 24 | 19 | <0.01 |
| Weight for height < P10 | 22 | 49 | 34 | <0.01 |
| Height for age < P10 | 42 | 34 | 32 | <0.01* |
| Abdominal pain | 7 | 16 | 50 | <0.01 |
| Lassitude | Not known | 12 | 24 | <0.01 |
| Anorexia | 0 | 5 | 24 | <0.01 |
| Age ≤ 2 yr. | 60 | 47 | 30† | <0.01 |
| Median age (yr.) | 1.5 | 2.1 | 5.8† | <0.01 |
* Comparison of data only significantly different between 1975–1990 and 2010–2013
† Age of all 1107 reported CD children