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. 2021 Jul 16;11:14611. doi: 10.1038/s41598-021-93998-9

Table 1.

Correlation between CTSA expression and clinical outcomes in HCC patients (373 cases, TCGA database).

Characteristics CTSA level
N High (n) Low (n) P-value*
Gender
Male 251 130 121 0.358
Female 122 57 65
Age (years)
 > 55 246 127 119 0.423
 <  = 55 127 60 67
Vascular invasion
Yes 139 84 53 0.001
No 234 103 133
TNM staging
I/II 268 122 146 0.004
III/IV 105 65 40
Serum AFP level (ng/ml)
> 400 ng/ml 133 82 51 0.001
<  = 400 ng/ml 240 105 135
Neoplasm histology grades
G1/G2 227 104 123 0.038
G3/G4 146 83 63
Famliy cancer history
Yes 115 65 50 0.068
No 209 96 113
Adjancent hepatic inflammation
Yes 174 73 101 0.009
No 154 87 67
Radiation
Yes 22 15 7 0.081
No 341 172 169
Pharmaceutical
Yes 42 25 17 0.196
No 331 162 169
BMI (kg/m2)
>  = 24 178 95 83 0.396
< 24 158 77 81