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. 2021 Jul 16;11:14611. doi: 10.1038/s41598-021-93998-9

Table 3.

Correlation between CTSA expression and clinical outcomes in HCC patients (n = 136).

Characteristics CTSA level
N High (n) Low (n) P-value*
Age (year)
> 55 70 48 42 0.589
<  = 55 66 22 24
Gender
Male 119 59 60 0.304
Female 17 11 6
Tumor size (cm)
> 5 cm 71 37 34 0.506
<  = 5 cm 65 33 32
TNM staging
I/II 88 39 49 0.024
III 48 31 17
Serum AFP level
> 400 ng/ml 63 42 21 0.001
<  = 400 ng/ml 73 28 45
Tumor location
Left 44 28 16 0.037
Right 92 42 50
Tumor differentiation
Low 14 9 5 0.031
Median 97 53 44
High 25 8 17
Vascular invasion
Yes 68 36 32 0.432
No 68 34 34
Tumor encapsulation
Yes 51 42 48 0.083
No 191 28 18
Recurrence
Yes 74 45 29 0.013
No 62 25 37
Survival
Alive 79 35 44 0.036
Dead 57 35 22