Table 5.
The main GO and KEGG pathway enrichment analysis for 117 co-expressed genes.
| Category | ID term | Term | Count | P value | Benjamini | FDR |
|---|---|---|---|---|---|---|
| GOTERM_Biological Process | GO:0015991 | ATP hydrolysis coupled proton transport | 7 | 5.78E−08 | 2.32E−05 | 2.31E−05 |
| GOTERM_Biological Process | GO:0005975 | Carbohydrate metabolic process | 6 | 5.19E−04 | 6.61E−02 | 6.58E−02 |
| GOTERM_Biological Process | GO:0006689 | Ganglioside catabolic process | 3 | 6.93E−04 | 6.61E−02 | 6.58E−02 |
| GOTERM_Biological Process | GO:0006880 | Intracellular sequestering of iron ion | 3 | 6.93E−04 | 6.61E−02 | 6.58E−02 |
| GOTERM_Biological Process | GO:0007040 | Lysosome organization | 4 | 8.22E−04 | 6.61E−02 | 6.58E−02 |
| GOTERM_Biological Process | GO:0006826 | Iron ion transport | 3 | 2.48E−03 | 1.66E−01 | 1.66E−01 |
| GOTERM_Biological Process | GO:0048147 | Negative regulation of fibroblast proliferation | 3 | 8.24E−03 | 4.73E−01 | 4.71E−01 |
| GOTERM_Biological Process | GO:0006897 | Endocytosis | 4 | 1.29E−02 | 6.50E−01 | 6.46E−01 |
| KEGG_PATHWAY | hsa04142 | Lysosome | 16 | 2.45E−14 | 2.72E−12 | 2.59E−12 |
| KEGG_PATHWAY | hsa04721 | Synaptic vesicle cycle | 7 | 1.58E−05 | 8.75E−04 | 8.35E−04 |
| KEGG_PATHWAY | hsa01100 | Metabolic pathways | 24 | 5.73E−05 | 1.81E−03 | 1.73E−03 |
| KEGG_PATHWAY | hsa05323 | Rheumatoid arthritis | 7 | 6.53E−05 | 1.81E−03 | 1.73E−03 |
| KEGG_PATHWAY | hsa00511 | Other glycan degradation | 4 | 5.29E−04 | 1.17E−02 | 1.12E−02 |
| KEGG_PATHWAY | hsa00520 | Amino sugar and nucleotide sugar metabolism | 5 | 7.80E−04 | 1.44E−02 | 1.38E−02 |
| KEGG_PATHWAY | hsa04145 | Phagosome | 7 | 1.03E−03 | 1.48E−02 | 1.41E−02 |
| KEGG_PATHWAY | hsa00190 | Oxidative phosphorylation | 7 | 1.07E−03 | 1.48E−02 | 1.41E−02 |