Table 4.

Predicted summary statistics of camrelizumab exposure metrics

	3 mg/kg every 2 weeks		200 mg every 2 weeks
	Median	2.5%–97.5%	Median	2.5%–97.5%
Cmax,ss (mg/L)	89.55	39.27–195.41	96.40	47.26–190.36
Cmin,ss (mg/L)	23.11	1.22–92.70	26.13	1.78–90.96
Caverage,ss (mg/L)a	41.27	12.81–113.87	45.48	15.28–112.08

C_max,ss steady-state peak concentration, C_min,ss, steady-state trough concentration, C_average,ss steady-state average concentration.

^a$C_{\mathrm{average,ss}}=\frac{{\mathrm{AUC}}_{\mathrm{ss}}\left(\mathrm{mg}\times \mathrm{weeks/L}\right)}{\mathrm{dosing}\mathrm{interval}\left(\mathrm{weeks}\right)},$