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. 2021 Apr 15;42(8):1223–1234. doi: 10.1038/s41401-021-00664-x

Fig. 3. The effect of pinocembrin on t-PA-induced hemorrhagic transformation.

Fig. 3

Delayed t-PA treatment increased the incidence and severity of hemorrhage. Pinocembrin markedly decreased hemorrhage and the amount of hemoglobin. a Representative images of hemorrhagic transformation. b Hemoglobin content. c Representative images of H&E staining. The arrow indicates bleeding. The data are presented as the mean ± SEM. ##P < 0.01 and ###P < 0.001 compared with sham group; $P < 0.05 compared with the vehicle group; *P < 0.05 compared with the t-PA group; n = 5; bar = 100 µm.