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. 2021 Jul 16;11:14630. doi: 10.1038/s41598-021-94073-z

Table 2.

Area under the receiver operating curve for the association between baseline biomarkers and severe leptospirosis.

Parameters AUC ROC SE p value 95% CI Cut-off Sensitivity Specificity
Leptospiremia 0.61 0.04 0.010* 0.52–0.70 953 0.59 0.67
MAT titer 0.40 0.20 0.594 0.00–0.80 600 0.83 0.25
NGAL 0.75 0.04 < 0.001 0.67–0.82 360 0.62 0.78
IL-6 0.75 0.04 < 0.001 0.67–0.82 121 0.64 0.74

AUC/ROC area under curve of receiver operating curve, SE standard error, CI confidence interval, Sens sensitivity, Spec specificity, pNGAL plasma neutrophil gelatinase-associated lipocalin, IL-6 interleukin 6, MAT microscopic agglutination test.