Table 2.
Area under the receiver operating curve for the association between baseline biomarkers and severe leptospirosis.
| Parameters | AUC ROC | SE | p value | 95% CI | Cut-off | Sensitivity | Specificity |
|---|---|---|---|---|---|---|---|
| Leptospiremia | 0.61 | 0.04 | 0.010* | 0.52–0.70 | 953 | 0.59 | 0.67 |
| MAT titer | 0.40 | 0.20 | 0.594 | 0.00–0.80 | 600 | 0.83 | 0.25 |
| NGAL | 0.75 | 0.04 | < 0.001 | 0.67–0.82 | 360 | 0.62 | 0.78 |
| IL-6 | 0.75 | 0.04 | < 0.001 | 0.67–0.82 | 121 | 0.64 | 0.74 |
AUC/ROC area under curve of receiver operating curve, SE standard error, CI confidence interval, Sens sensitivity, Spec specificity, pNGAL plasma neutrophil gelatinase-associated lipocalin, IL-6 interleukin 6, MAT microscopic agglutination test.