Table 1.
Frequency of mutation in RAS isoforms in selected human cancers.
| Cancer type | KRAS (%) | NRAS (%) | HRAS (%) | Total (%) |
|---|---|---|---|---|
| PAAD | 75 | <1 | <1 | 76 |
| COAD | 43 | 5 | 2 | 53 |
| READ | 42 | 11 | 0 | 53 |
| UCEC | 25 | 8 | 2 | 35 |
| LUAD | 28 | <1 | <1 | 29 |
| SKCM | 2 | 28 | 2 | 33 |
| UCS | 12 | 2 | 0 | 14 |
| THYM | 1 | 3 | 9 | 13 |
| THCA | 1 | 8 | 3 | 12 |
| STAD | 9 | 1 | 1 | 11 |
| PCPG | 0 | 0 | 10 | 10 |
The results shown here are in whole or part based upon data generated by the TCGA Research Network: https://www.cancer.gov/tcga.
PAAD pancreatic adenocarcinoma, COAD colon adenocarcinoma, READ rectum adenocarcinoma, UCEC uterine Corpus endometrial carcinoma, SKCM skin cutaneous melanoma, LUAD lung adenocarcinoma, UCS uterine carcinosarcoma, THYM thymoma, THCA thyroid carcinoma, STAD stomach adenocarcinoma, PCPG pheochromocytoma and paraganglioma.