MIC^a of GN1 and GP1 towards further MDR and non-MDR bacterial strains.

	GN1	GP1	Polymyxin B
P. aeruginosa ZEM-1Ab,c	4	4	0.5
P. aeruginosa ZEM9Ab,c	64	64	4
P. aeruginosa PA14c	2	8–16	<0.5
P. aeruginosa PA14 4.13 (phoQ)c,d	2	8–16	1
P. aeruginosa PA14 4.18 (pmrB)c,d	4	32–64	2
P. aeruginosa PA14 2P4 (pmrB)c,d	8	64	2
S. maltophilia b , c	4	16	0.5
E. cloacae b , c	8	16–32	1
K. pneumoniae (OXA-48)b,c	>64	16–32	1
K. pneumoniae NCTC148b,c	>64	32	1
B. cenocepacia b , c	>64	>64	>64
S. epidermidis b , e	16	16	32–64

^aThe MIC was determined in Müller–Hinton medium after 16–20 h of incubation at 37 °C. Each result represents two independent experiments performed in duplicate.

^bMDR strains.

^cGram-negative strains.

^dStrains carrying spontaneous mutations in the indicated genes, all leading to polymyxin B resistance.

^eGram-positive strain.