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. 2020 Sep 16;42(8):1256–1266. doi: 10.1038/s41401-020-00516-0

Fig. 3. Melittin induced no significant in vivo toxicity in mice treated with the effective dose.

Fig. 3

The in vivo toxicity was evaluated in healthy C57BL/6 mice. a–e Mean body weights of the model mice treated with melittin. Hematological parameters, including WBCs, RBCs, HGB, and PLTs, were measured. f–i Blood biochemical parameters, including ALT, AST, UREA, and total bilirubin, were measured. j Representative images of hematoxylin-eosin-stained liver, kidney, heart, lung, and cortex tissues under a ×40 microscope. n = 5 mice per group. a–i Group comparisons had no statistical significance.