Table 3.
Serum lipid profile in healthy controls and Parkinson’s disease cohorts.
| HCs | sPD | GBA-PD | LRRK2-PD | F value | P value | |
|---|---|---|---|---|---|---|
| TC (mg/dl), mean ± SD | 202.15 ± 38.11 | 195.76 ± 42.68 | 178.22 ± 34.47 | 213.73 ± 30.01 | 4.99 | 0.002** |
| HDL (mg/dl), mean ± SD | 58.37 ± 17.25 | 60.46 ± 17.77 | 56.11 ± 14.25 | 56.22 ± 12.32 | 1.03 | 0.38 |
| LDL (mg/dl), mean ± SD | 127.49 ± 30.44 | 125.75 ± 40.65 | 105.78 ± 29.85 | 141.09 ± 30.48 | 3.85 | 0.01* |
| TG (mg/dl), mean ± SD | 115.59 ± 70.14 | 102.03 ± 59.63 | 105.39 ± 42.84 | 110.19 ± 63.46 | 2.06 | 0.10 |
TC total cholesterol, HDL high-density lipoprotein, LDL low-density lipoprotein, TG triglycerides, HCs healthy controls, sPD sporadic Parkinson’s disease patients, GBA-PD GBA-associated Parkinson’s disease patients, LRRK2-PD LRRK2-associated Parkinson’s disease patients, SD standard deviation.
Analysis of covariance (ANCOVA), adjusting by sex and age, was applied. **p<0.005 *p<0.05.