Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2021 Jul 16;12:4369. doi: 10.1038/s41467-021-24662-z

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© The Author(s) 2021

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

PMC Copyright notice

Fig. 4 — a The Si-C calculated intact genome 3D structures of cell 1 at 100, 10, and 1 kb resolution with an expanded view of the separated chromosome territories along with the published NucDynamics 100-kb resolution structure of cell 1. The 100-kb resolution structures of NucDynamics are downloaded from GEO with accession code GSE80280. b Cross-sections of intact genome 3D structures of cell 1, colored according to whether the sequence is in the A (red) or B (blue) compartment (first column); whether the sequence is part of a lamina-associated domain (LAD) (blue) or not (red) (second column); the CpG density from red to blue (high to low) (third column); the replication time in the DNA duplication process from red to blue (early to late) (fourth column). c The Si-C calculated 10-kb resolution intact genome 3D structure of cell 1 with an expanded view of the spatial distribution of the A (red) and B (blue) compartments. d The Si-C calculated 10-kb resolution structures of chromosome 17 of cells 1 and 3 colored from red to blue (centromere to telomere) with structures of other chromosomes shown as black dots.