Table 4.

Prognostic models for DFS and OS by Cox multivariate regression analysis. (Model 1: variables that were independent risk factors of PNI were included; Model 2: variables that were independent risk factors of ALBI were included).

Indicators	Model 1				Model 2
	OS		DFS		OS		DFS
	HR (95% CI)	P	HR (95% CI)	P	HR (95% CI)	P	HR (95% CI)	P
PLT	1.411 (1.125–1.770)	0.003	1.207 (1.002–1.454)	0.047	1.376 (1.098–1.724)	0.006	1.270 (1.058–1.525)	0.010
AFP	1.591 (1.301–1.944)	< 0.001			1.595 (1.305–1.949)	< 0.001
max-D	1.672 (1.345–2.078)	< 0.001	1.563 (1.310–1.864)	< 0.001	1.682 (1.354–2.090)	< 0.001
Number	1.369 (1.070–1.751)	0.012	1.566 (1.264–1.940)	< 0.001	1.364 (1.067–1.743)	0.013	1.540 (1.245–1.904)	< 0.001
DD	1.466 (1.200–1.790)	< 0.001	1.280 (1.079–1.517)	< 0.001	1.465 (1.200–1.788)	< 0.001	1.268 (1.071–1.502)	0.006
MVI	1.525 (1.234–1.885)	< 0.001	1.491 (1.238–1.795)	< 0.001	1.515 (1.226–1.871)	< 0.001	1.612 (1.342–1.937)	< 0.001
SF	1.924 (1.487–2.489)	< 0.001	1.633 (1.291–2.064)	< 0.001	1.907 (1.475–2.466)	< 0.001	1.690 (1.339–2.133)	< 0.001
PNI	1.314 (1.063–1.623)	0.011	1.220 (1.015–1.466)	0.034
ALBI					1.272 (1.045–1.549)	0.017	1.191 (1.010–1.404)	0.038