Table 5.

Circadian analysis of telemetry data from flox and HBK mice

	Flox			HBK
Parameter	Mesor	Amplitude	Period	Mesor	Amplitude	Period
Systolic blood pressure	128 ± 1	22.3 ± 0.6	23.93 ± 0.03	125 ± 1*	24.5 ± 1.6	23.95 ± 0.02
Diastolic blood pressure	88 ± 1	24.0 ± 3.5	23.92 ± 0.06	90 ± 2	20.7 ± 1.3	23.94 ± 0.03
Mean arterial pressure	109 ± 1	21.1 ± 1.2	23.93 ± 0.05	108 ± 1	21.9 ± 1.3	23.95 ± 0.02
Heart rate	594 ± 10	83.7 ± 10.1	23.80 ± 0.16	598 ± 10	78.9 ± 6.2	23.86 ± 0.06

Values are presented as means ± SE; n = 4. Unpaired Student’s t test. Symbols indicate statistically significant differences (P < 0.05) between genotypes. HBK, hepatocyte-specific Bmal1 knockout.

*P < 0.05 HBK vs. flox mice.