Figure 6.

Perinatal exposure to an ERα or ERβ agonist masculinized female MSN evoked action potential firing rate. A: AP firing rate evoked by depolarizing current injection. AP firing rate was masculinized in MSNs recorded from females with perinatal exposure to the ERα agonist PPT and the ERβ agonist DPN. B: the slope of the evoked AP firing rate to depolarizing current injection curve (FI Slope) was masculinized in MSNs recorded from females with perinatal exposure to the ERα agonist PPT and the ERβ agonist DPN. C: AP threshold values were hyperpolarized in MSNs recorded from females with perinatal exposure to the ERα agonist PPT and the GPER-1 agonist G1. AP, action potential; ER, estrogen receptor; MSN, medium spiny neuron. #P = 0.0876; *P < 0.05; **P < 0.01.