Table 3.
Multivariate logistic regression analysis of the training dataset
| Variable | Overall early-death | Cancer-specific early-death | ||||
|---|---|---|---|---|---|---|
| OR | 95% CI | P | OR | 95% CI | P | |
| Gender | ||||||
| Male | Ref | Ref | ||||
| Female | 0.742 | 0.703–0.783 | < 0.001 | 0.773 | 0.731–0.817 | < 0.001 |
| Age | ||||||
| < 40 | Ref | Ref | ||||
| 40–49 | 1.715 | 1.133–2.596 | 0.011 | 1.558 | 1.011–2.4 | 0.044 |
| 50–59 | 2.634 | 1.769–3.923 | < 0.001 | 2.377 | 1.57–3.597 | < 0.001 |
| 60–69 | 3.494 | 2.35–5.197 | < 0.001 | 3.144 | 2.08–4.51 | < 0.001 |
| 70–79 | 5.296 | 3.559–7.881 | < 0.001 | 4.634 | 3.065–7.007 | < 0.001 |
| > =80 | 7.726 | 5.162–11.563 | < 0.001 | 6.176 | 4.062–9.389 | < 0.001 |
| Race | ||||||
| White | Ref | Ref | ||||
| Black | 0.941 | 0.867–1.022 | 0.151 | 0.923 | 0.847–1.005 | 0.064 |
| Other | 0.728 | 0.657–0.806 | < 0.001 | 0.733 | 0.659–0.816 | < 0.001 |
| Histology | ||||||
| AD | Ref | Ref | ||||
| SQCC | 1.555 | 1.425–1.697 | < 0.001 | 1.477 | 1.351–1.614 | < 0.001 |
| LCLC | 1.188 | 0.994–1.42 | 0.058 | 1.178 | 0.981–1.415 | 0.08 |
| SCLC | 0.975 | 0.901–1.056 | 0.541 | 0.96 | 0.885–1.043 | 0.336 |
| Other | 1.434 | 1.336–1.539 | < 0.001 | 1.315 | 1.223–1.414 | < 0.001 |
| Gleason grade | ||||||
| I | Ref | Ref | ||||
| II | 1.106 | 0.865–1.413 | 0.423 | 1.146 | 0.887–1.482 | 0.297 |
| III | 1.669 | 1.322–2.108 | < 0.001 | 1.673 | 1.31–2.136 | < 0.001 |
| IV | 1.555 | 1.187–2.038 | < 0.001 | 1.614 | 1.218–2.137 | 0.001 |
| Unknown | 1.446 | 1.148–1.800 | 0.002 | 1.412 | 1.109–1.799 | 0.005 |
| T Stage | ||||||
| T0 | Ref | Ref | ||||
| T1 | 0.951 | 0.71–1.273 | 0.734 | 1.334 | 0.951–1.872 | 0.095 |
| T2 | 1.221 | 0.919–1.624 | 0.169 | 1.787 | 1.283–2.489 | 0.001 |
| T3 | 1.512 | 1.137–2.01 | 0.004 | 2.138 | 1.535–2.978 | < 0.001 |
| T4 | 1.662 | 1.252–2.208 | < 0.001 | 2.389 | 1.717–3.323 | < 0.001 |
| Tx | 1.675 | 1.255–2.236 | < 0.001 | 2.247 | 1.608–3.141 | < 0.001 |
| N Stage | ||||||
| N0 | Ref | Ref | ||||
| N1 | 0.877 | 0.786–0.979 | 0.019 | 0.904 | 0.806–1.013 | 0.082 |
| N2 | 1.13 | 1.053–1.212 | 0.001 | 1.146 | 1.065–1.232 | < 0.001 |
| N3 | 1.108 | 1.018–1.207 | 0.018 | 1.145 | 1.048–1.25 | 0.003 |
| Nx | 1.257 | 1.107–1.426 | < 0.001 | 1.212 | 1.065–2.38 | 0.004 |
| Bone Met | ||||||
| Yes | Ref | Ref | ||||
| None | 0.791 | 0.746–0.839 | < 0.001 | 0.795 | 0.748–0.844 | < 0.001 |
| Unknown | 0.82 | 0.665–1.011 | 0.063 | 0.742 | 0.597–0.921 | 0.007 |
| Liver Met | ||||||
| Yes | Ref | Ref | ||||
| None | 0.566 | 0.529–0.605 | < 0.001 | 0.594 | 0.555–0.635 | < 0.001 |
| Unknown | 0.734 | 0.607–0.887 | 0.001 | 0.816 | 0.672–0.989 | 0.039 |
| Marital | ||||||
| Single | Ref | Ref | ||||
| Married | 0.757 | 0.717–0.8 | < 0.001 | 0.779 | 0.736–0.824 | < 0.001 |
| Unknown | 0.897 | 0.781–1.03 | 0.122 | 0.836 | 0.723–0.965 | 0.015 |