Table 3.
Association of TyG index with arterial stiffness in Cox proportional hazard models
TyG index | Arterial stiffness(n) | Incident rate (per 1000 person-years) | Model 1 | Model 2 | ||
---|---|---|---|---|---|---|
HR (95%CI) | P value | HR (95%CI) | P value | |||
Overall | 883 | 32.90 | 1.46 (1.34–1.58) | < 0.001 | 1.22 (1.10–1.35) | < 0.001 |
Q1 (6.81–8.06) | 106 | 14.46 | Reference | Reference | ||
Q2 (8.06–8.48) | 181 | 26.21 | 1.39 (1.09–1.77) | 0.008 | 1.27 (1.00–1.62) | 0.052 |
Q3 (8.48–8.98) | 285 | 44.78 | 2.05 (1.64–2.57) | < 0.001 | 1.69 (1.35–2.12) | < 0.001 |
Q4 (8.98–13.17) | 311 | 49.87 | 2.30 (1.84–2.87) | < 0.001 | 1.58 (1.25–2.01) | < 0.001 |
N = 5348; TyG index, triglyceride–glucose index; HR, hazard ratio; CI, confidence interval; Q, quartiles
Model 1, adjusted for age and sex at baseline
Model 2, adjusted for variables in model 1 plus smoking, alcohol drinking, physical activity, MAP, diabetes, hs-CRP, and BMI at baseline