Table 5.
Logistic regression of risk factors of colonization throughout the treatment
| Patient characteristics | Univariate | Multivariate | ||
|---|---|---|---|---|
| OR (95 %CI) | p value | OR (95 %CI) | p value | |
| Sex | ||||
| Male | 1 | |||
| Female | 1.42 (0.49–4.12) | 0.523 | ||
| Age | 1.03 (0.99–1.08) | 0.168* | 1.06 (1.01–1.123) | 0.021# |
| Underlying disease | ||||
| DM | 0.52 (0.08–3.36) | 0.496 | ||
| HT | 0.78 (0.27–2.23) | 0.641 | ||
| Tumor site | ||||
| Nasopharynx | 1 | |||
| Oropharynx | 1.10 (0.33–3.60) | 0.880 | ||
| Oral cavity | 0.84 (0.26–2.69) | 0.770 | ||
| Radiotherapy option | ||||
| Postoperative RT | 1 | |||
| Radical RT | 1.15 (0.42–3.14) | 0.790 | ||
| Dose of radiotherapy (Gy) | 1.08(1.01–1.16) | 0.031* | ||
| CCRT | 3.41 (1.16–9.99) | 0.026* | 4.29 (1.12–16.49) | 0.034# |
| CCRT cycle | 1.06 (0.64–1.78) | 0.820 | ||
| Type of chemotherapy agent | ||||
| Cisplatin | 1 | |||
| Carboplatin | 1.16 (0.36–3.80) | 0.798 | ||
| Personal history | ||||
| Smoking | ||||
| Never used | 1 | |||
| Using currently | 0.82 (0.26–2.56) | 0.727 | ||
| Alcohol | ||||
| Never used | 1 | |||
| Using urrently | 1.54 (0.58–4.09) | 0.387 | ||
| Oral status | ||||
| Oral hygiene | ||||
| Excellent/good | 1 | |||
| Fair/poor | 0.68 (0.20–2.25) | 0.527 | ||
| Denture wearer | 0.41 (0.10–1.68) | 0.216 | ||
| Mouthwash using | ||||
| Non-benzydamine HCl | 1 | |||
| Benzydamine HCl | 1.05 (0.35–3.10) | 0.934 | ||
| 2% viscous lidocaine solution using | 2.91 (1.03–8.18) | 0.043* | 3.62 (1.15–11.34) | 0.027# |
| Xerostomia | 3.51 (0.74–16.70) | 0.115* | ||
| Mucositis | 2.85 (1.01–8.03) | 0.048* | ||
| Candida colonization before RT | 4.32 (1.32–14.14) | 0.016* | ||
*p < 0.25, # significant risk factors