Table 2.
Migraine characteristics
| EM N = 8 |
CM N = 7 |
P value | |
|---|---|---|---|
| Headache frequencyb, mean (SD), days/month | 8.8 (1.8) | 24.7 (6.3) | < 0.0001 |
| Disease durationb, mean (SD), years | 28.4 (13.2) | 20.0 (19.5) | 0.343 |
| Chronification, median (IQR), years | -- | 4.0 (11.0) | -- |
| Auraa, n (%) | 3 (37.5) | 4 (57.1) | 0.619 |
| Unilateral Paina, n (%) | 5 (62.5) | 7 (100.0) | 0.200 |
| Analgesic Usec, median (IQR), days/month | 0.5 (8.8) | 5.0 (8.0) | 0.613 |
| MIDASc, median (IQR) | 9.5 (29.0) | 32.0 (89.0) | 0.029 |
| HIT-6b, mean (SD) | 60.5 (3.9) | 61.3 (4.9) | 0.735 |
|
MSQb, mean (SD) Role Function preventive Role function restrictive Emotional function |
53.1 (23.8) 47.9 (17.1) 51.4 (27.2) |
51.8 (15.8) 50.0 (13.3) 59.5 (16.3) |
0.800 0.901 0.503 |
Bold font in the P values column indicates statistically significant
aSignificance assessed with Fisher’s exact test
bSignificance assessed with independent t-test
cSignificance assessed with Mann-Whitney U test
HC healthy controls; EM episodic Migraine; CM chronic migraine; SD standard deviation; IQR interquartile range; y years; d/mo days per month; MIDAS migraine disability assessment; HIT6 headache impact test 6; MSQ migraine-specific quality-of-life