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. 2021 Jul 16;21:344. doi: 10.1186/s12872-021-01997-5

Table 3.

The results for KEGG analysis in stable CAD patients compared to healthy subjects

Gene set Description Size Leading edge number ES NES P value FDR
hsa04621 NOD-like receptor signaling pathway 8 6 − 0.77061 − 2.0947 0.0014245 0.0039551
hsa04060 Cytokine-cytokine receptor interaction 7 4 − 0.77594 − 1.9948 0.001462 0.0050427
hsa05132 Salmonella infection 5 4 − 0.87092 − 2.0026 0 0.0051911
hsa04657 IL-17 signaling pathway 7 6 − 0.8278 − 2.1093 0 0.0051911
hsa04010 MAPK signaling pathway 7 6 − 0.7715 − 1.9341 0.0014451 0.006427
hsa04151 PI3K-Akt signaling pathway 7 5 − 0.71874 − 1.855 0.005571 0.0084046
hsa05167 Kaposi sarcoma-associated herpesvirus infection 7 4 − 0.72723 − 1.8713 0.0028011 0.0085282
hsa04064 NF-kappa B signaling pathway 8 6 − 0.79671 − 2.1169 0.0013966 0.008899
hsa04668 TNF signaling pathway 9 8 − 0.67798 − 1.8731 0.002751 0.0097465
hsa05163 Human cytomegalovirus infection 5 3 − 0.77931 − 1.7897 0.004644 0.017353
hsa04620 Toll-like receptor signaling pathway 5 3 − 0.74322 − 1.7044 0.01682 0.028378
hsa05142 Chagas disease (American trypanosomiasis) 5 3 − 0.74322 − 1.7044 0.01682 0.028378
hsa05200 Pathways in cancer 7 6 − 0.6674 − 1.7301 0.011561 0.029528
hsa04932 Non-alcoholic fatty liver disease (NAFLD) 5 4 − 0.74563 − 1.7086 0.006006 0.032059
hsa04625 C-type lectin receptor signaling pathway 5 3 − 0.74881 − 1.7165 0.010753 0.032259
hsa04380 Osteoclast differentiation 7 7 − 0.65041 − 1.6467 0.016129 0.04088

KEGG, Kyoto encyclopedia of genes and genomes; CAD, coronary artery disease; FDR, false discovery rate