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. 2021 Jul 9;118(28):e2013164118. doi: 10.1073/pnas.2013164118

Table 2.

Age-, sex-, and male circumcision status–specific incidence rates per 100 py and IRRs comparing the periods before (2004 to 2015) and after (2016 to 2019) UTT went into effect

Sex Age-group Incidence rate (per 100 py) IRR
2004 to 2015 2016 to 2019
Women 15 to 19 5.32 (4.87 to 5.79) 3.00 (2.33 to 3.77) 0.56 (0.43 to 0.73)
20 to 24 6.73 (6.27 to 7.20) 5.12 (4.25 to 6.37) 0.76 (0.62 to 0.96)
25 to 29 5.96 (5.37 to 6.65) 4.53 (3.52 to 5.88) 0.76 (0.56 to 1.02)
30 to 34 4.17 (3.50 to 4.99) 4.01 (2.78 to 5.66) 0.96 (0.64 to 1.42)
35 to 39 1.94 (1.50 to 2.47) 1.74 (0.95 to 3.09) 0.89 (0.46 to 1.71)
40 to 49 1.55 (1.32 to 1.83) 1.00 (0.59 to 1.73) 0.64 (0.36 to 1.15)
Men 15 to 19 0.92 (0.72 to 1.16) 0.32 (0.14 to 0.71) 0.36 (0.15 to 0.82)
20 to 24 2.74 (2.40 to 3.13) 0.87 (0.51 to 1.53) 0.32 (0.18 to 0.59)
25 to 29 3.91 (3.32 to 4.55) 2.13 (1.24 to 3.64) 0.54 (0.31 to 0.94)
30 to 34 3.26 (2.59 to 4.12) 2.78 (1.68 to 4.57) 0.85 (0.49 to 1.46)
35 to 39 2.62 (1.87 to 3.60) 1.71 (0.65 to 4.24) 0.66 (0.22 to 1.71)
40 to 54 1.43 (1.12 to 1.80) 0.86 (0.00-Inf) 0.68 (0.00-Inf)
Men (circumcised)* 15 to 19 0.52 (0.35 to 0.76) 0.22 (0.11 to 0.48) 0.43 (0.21 to 0.95)
20 to 24 1.58 (1.12 to 2.24) 0.60 (0.33 to 1.06) 0.38 (0.22 to 0.67)
25 to 29 2.24 (1.52 to 3.24) 1.38 (0.76 to 2.41) 0.62 (0.36 to 1.09)
30 to 34 1.89 (1.26 to 2.84) 1.74 (0.99 to 3.08) 0.92 (0.54 to 1.56)
35 to 39 1.50 (0.94 to 2.37) 1.11 (0.41 to 2.94) 0.75 (0.27 to 2.06)
40 to 54 0.82 (0.53 to 1.20) 0.18 (0.00-Inf) 0.21 (0.00-Inf)
Men (uncircumcised)* 15 to 19 0.93 (0.74 to 1.18) 0.40 (0.19 to 0.84)
20 to 24 2.82 (2.48 to 3.21) 1.08 (0.63 to 1.84)
25 to 29 4.02 (3.38 to 4.69) 2.46 (1.49 to 4.20)
30 to 34 3.37 (2.64 to 4.32) 3.06 (1.99 to 5.04)
35 to 39 2.68 (1.96 to 3.66) 1.98 (0.78 to 5.20)
40 to 54 1.44 (1.13 to 1.84) 0.30 (0.00-Inf)

IRR = incidence rate ratio comparing age-specific incidence in the UTT era (2016 to 2019) relative to age-specific incidence in the pre-UTT era (2004 to 2015). Bold IRRs indicate significance at alpha < 0.05.

*

Incidence rates for circumcised and uncircumcised men are estimated by fitting a generalized linear model with an indicator for individual-level circumcision status (circumcision model). Fitted IRR’s from the circumcision model are adjusted for circumcision status without an interaction term and so are equivalent for both uncircumcised and circumcised men.