Table 3.
Comparison of Clinical Data and Biochemical Indexes Before and After Exenatide Treatment in Case Group (x ± s)
| Variables | Exenatide-Pre (n=30) | Exenatide-Post (n=30) | t values | P values |
|---|---|---|---|---|
| Weight (kg) | 87.93±13.70 | 83.10±14.36 | 4.626 | 0.002 |
| BMI (kg/m2) | 29.58±3.33 | 27.92±3.27 | 3.524 | 0.016 |
| Waist (cm) | 105.37±9.77 | 99.22±9.4 | 5.912 | <0.001 |
| SBP (mmHg) | 136.60±9.26 | 131.33±8.81 | 2.256 | 0.028 |
| DBP (mmHg) | 88.23±11.45 | 87.71±10.92 | 0.416 | 0.671 |
| TCH (mmol/L) | 4.64±1.06 | 3.78±0.75 | 3.271 | 0.031 |
| TG (mmol/L) | 2.92±1.83 | 1.82±0.72 | 4.317 | 0.009 |
| LDL-C (mmol/L) | 2.56±0.80 | 2.19±0.66 | 2.925 | 0.048 |
| HDL-C mmol/L) | 0.99±0.30 | 1.08±0.21 | 2.968 | 0.041 |
| FPG (mmol/L) | 11.67±4.06 | 6.90±1.20 | 6.891 | <0.001 |
| HbA1c (%) | 8.81±1.09 | 7.01±1.11 | 5.885 | <0.001 |
| NO (μmol/L) | 68.1±14.7 | 89.6±15.8 | 6.336 | <0.001 |
Abbreviations: BMI, body mass index; SBP, systolic blood pressure; DBP, diastolic blood pressure; TCH, total cholesterol; TG, triglycerides; LDL-C, low-density lipoprotein cholesterol; HDL-C, high-density lipoprotein cholesterol; FPG, fasting plasma glucose; HbA1c, hemoglobin A1c; NO, nitric oxide; Exenatide-pre, before exenatide treatment; Exenatide-post, after exenatide treatment.