Table 4.
Comparison of Coagulation Function and Platelet Aggregation Function Before and After Exenatide Treatment in Case Group (
±s)
| Variables | Exenatide-Pre (n=30) | Exenatide-Post (n=30) | t values | P values |
|---|---|---|---|---|
| PLT (×1012 g/L) | 211.02±52.29 | 218.03±53.82 | 0.292 | 0.728 |
| PT (s) | 11.86±1.58 | 11.65±1.30 | 0.325 | 0.581 |
| PTA (%) | 105.93±12.05 | 107.05±12.95 | 0.443 | 0.476 |
| INR | 1.31±1.81 | 1.29±1.84 | 0.298 | 0.711 |
| APTT (s) | 40.08±43.75 | 32.90±4.33 | 1.901 | 0.104 |
| FIB (g/L) | 3.38±0.78 | 2.89±0.63 | 2.951 | 0.044 |
| TT (s) | 16.59±1.37 | 17.14±3.06 | 0.521 | 0.382 |
| FDP (μg/mL) | 1.78±1.51 | 1.66±1.11 | 1.037 | 0.165 |
| DD (μg/mL) | 0.37±0.45 | 0.29±0.30 | 0.783 | 0.321 |
| CD62p (%) | 15.14±2.26 | 10.45±1.27 | 8.538 | <0.001 |
| PAC-1 (%) | 28.67±1.62 | 19.25±1.57 | 24.797 | <0.001 |
| EPI induction (%) | 77.90±6.31 | 61.96±8.94 | 11.515 | <0.001 |
| COLL induction (%) | 61.63±7.84 | 59.4±6.40 | 1.486 | 0.148 |
| ADP induction (%) | 52.89±9.36 | 49.01±5.99 | 1.893 | 0.068 |
| AA induction (%) | 76.09±3.14 | 50.98±6.73 | 17.754 | <0.001 |
Abbreviations: PLT, platelets; PT, prothrombin time; PTA, prothrombin time activity; INR, international normalized ratio; APTT, activated partial thromboplastin time; FIB, fibrinogen; TT, thrombin time; FDP, fibrin degradation products; DD, D-dimer; PAC-1, platelet activation complex-1; EPI, epinephrine; COLL, collagen; ADP, adenosine diphosphate; AA, arachidonic acid; Exenatide-pre, before exenatide treatment; Exenatide-post, after exenatide treatment.