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GSDME is dispensable for macrophage pyroptosis and cytokine secretion upon Yptb infection. (A and B) Unprimed or (C and D) LPS-primed BMDMs were infected with Yptb for the (A, B, and D) indicated time points or (C) for 3 h. (A) Mixed supernatant and cell extracts were examined by immunoblotting. (A–D) Immunoblots are representative of three independent experiments. (B and C) Data are mean + SEM of pooled data from four independent experiments. *P < 0.05, **P < 0.01.
