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. 2021 Jul 17;11(7):133. doi: 10.1038/s41408-021-00525-0

Table 2.

Cumulative incidence estimates of treatment initiation, transformation to DLBCL before treatment, and death without therapy based on the duration of W/W strategy.

Time from start of W/W FL status Likelihood (point estimates) in the next 1 year (95% CI) Likelihood (point estimates) in the next 2 years (95% CI) Likelihood (point estimates) in the next 5 years (95% CI) Likelihood (point estimates) in the next 10 years (95% CI)
Diagnosis Transformation prior to therapy 0.01 (0.00, 0.03) 0.03 (0.01, 0.05) 0.06 (0.04, 0.09) 0.09 (0.06, 0.13)
Initiation of therapy 0.16 (0.13, 0.20) 0.26 (0.22, 0.31) 0.43 (0.38, 0.48) 0.48 (0.43, 0.54)
Death without therapy 0.01 (0.00, 0.03) 0.02 (0.01, 0.04) 0.04 (0.03, 0.07) 0.06 (0.04, 0.10)
2 years Transformation 0.02 (0.01, 0.04) 0.04 (0.02, 0.07) 0.06 (0.04, 0.10) 0.09 (0.06, 0.14)
Therapy 0.10 (0.07, 0.14) 0.18 (0.14, 0.23) 0.30 (0.25, 0.37) 0.39 (0.32, 0.48)
Death 0.01 (0.00, 0.03) 0.02 (0.01, 0.05) 0.04 (0.02, 0.07) 0.10 (0.06, 0.19)
4 years Transformation 0.02 (0.01, 0.05) 0.03 (0.01, 0.07) 0.05 (0.03, 0.11) 0.09 (0.04, 0.19)
Therapy 0.08 (0.05, 0.14) 0.13 (0.09, 0.19) 0.19 (0.14, 0.26) 0.36 (0.26, 0.50)
Death 0.01 (0.00, 0.04) 0.02 (0.01, 0.05) 0.02 (0.02, 0.06) 0.17 (0.09, 0.33)
5 years Transformation 0.01 (0.00, 0.05) 0.02 (0.01, 0.06) 0.06 (0.02, 0.13) 0.08 (0.04, 0.20)
Therapy 0.05 (0.03, 0.10) 0.09 (0.05, 0.16) 0.12 (0.07, 0.19) 0.31 (0.20, 0.47)
Death 0.01 (0.00, 0.05) 0.01 (0.00, 0.06) 0.04 (0.02, 0.11) 0.18 (0.09, 0.37)
6 years Transformation 0.01 (0.00, 0.06) 0.02 (0.00, 0.07) 0.05 (0.02, 0.12) 0.08 (0.03, 0.21)
Therapy 0.04 (0.02, 0.10) 0.07 (0.04, 0.14) 0.13 (0.07, 0.23) 0.28 (0.17, 0.45)
Death 0.02 (0.00, 0.06) 0.02 (0.00, 0.05) 0.06 (0.02, 0.16) 0.19 (0.09, 0.39)