Table 4.
Cumulative incidence estimates of treatment initiation, transformation to DLBCL before treatment, and death without therapy based on presence or absence of any treatment initiation criteria at diagnosis.
| Time from start of W/W | FL status | Likelihood (point estimates) in the next 1 year (95% CI) | Likelihood (point estimates) in the next 2 year (95% CI) | Likelihood (point estimates) in the next 5 year (95% CI) | Likelihood (point estimates) in the next 10 year (95% CI) |
|---|---|---|---|---|---|
| Total cohort | Transformation | 0.01 (0.00, 0.03) | 0.03 (0.01, 0.05) | 0.06 (0.04, 0.09) | 0.09 (0.06, 0.13) |
| Therapy | 0.16 (0.13, 0.20) | 0.26 (0.22, 0.31) | 0.43 (0.38, 0.48) | 0.48 (0.43, 0.54) | |
| Death | 0.01 (0.00, 0.03) | 0.02 (0.01, 0.04) | 0.04 (0.03, 0.07) | 0.06 (0.04, 0.10) | |
| Any treatment initiation criteria: positive | Transformation | 0.01 (0.00, 0.04) | 0.02 (0.01, 0.06) | 0.06 (0.04, 0.11) | 0.12 (0.07, 0.19) |
| Therapy | 0.15 (0.11, 0.21) | 0.27 (0.22, 0.34) | 0.44 (0.37, 0.51) | 0.48 (0.42, 0.56) | |
| Death | 0.01 (0.00, 0.04) | 0.02 (0.01, 0.05) | 0.03 (0.02, 0.07) | 0.06 (0.03, 0.12) | |
| Any treatment initiation criteria: negative | Transformation | 0.01 (0.00, 0.04) | 0.03 (0.01, 0.07) | 0.06 (0.03, 0.11) | 0.06 (0.03, 0.11) |
| Therapy | 0.15 (0.11, 0.21) | 0.24 (0.18, 0.31) | 0.42 (0.35, 0.50) | 0.49 (0.42, 0.57) | |
| Death | 0.01 (0.00, 0.04) | 0.03 (0.01, 0.07) | 0.05 (0.03, 0.10) | 0.06 (0.03, 0.12) |