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. 2021 Jul 17;11(7):133. doi: 10.1038/s41408-021-00525-0

Table 4.

Cumulative incidence estimates of treatment initiation, transformation to DLBCL before treatment, and death without therapy based on presence or absence of any treatment initiation criteria at diagnosis.

Time from start of W/W FL status Likelihood (point estimates) in the next 1 year (95% CI) Likelihood (point estimates) in the next 2 year (95% CI) Likelihood (point estimates) in the next 5 year (95% CI) Likelihood (point estimates) in the next 10 year (95% CI)
Total cohort Transformation 0.01 (0.00, 0.03) 0.03 (0.01, 0.05) 0.06 (0.04, 0.09) 0.09 (0.06, 0.13)
Therapy 0.16 (0.13, 0.20) 0.26 (0.22, 0.31) 0.43 (0.38, 0.48) 0.48 (0.43, 0.54)
Death 0.01 (0.00, 0.03) 0.02 (0.01, 0.04) 0.04 (0.03, 0.07) 0.06 (0.04, 0.10)
Any treatment initiation criteria: positive Transformation 0.01 (0.00, 0.04) 0.02 (0.01, 0.06) 0.06 (0.04, 0.11) 0.12 (0.07, 0.19)
Therapy 0.15 (0.11, 0.21) 0.27 (0.22, 0.34) 0.44 (0.37, 0.51) 0.48 (0.42, 0.56)
Death 0.01 (0.00, 0.04) 0.02 (0.01, 0.05) 0.03 (0.02, 0.07) 0.06 (0.03, 0.12)
Any treatment initiation criteria: negative Transformation 0.01 (0.00, 0.04) 0.03 (0.01, 0.07) 0.06 (0.03, 0.11) 0.06 (0.03, 0.11)
Therapy 0.15 (0.11, 0.21) 0.24 (0.18, 0.31) 0.42 (0.35, 0.50) 0.49 (0.42, 0.57)
Death 0.01 (0.00, 0.04) 0.03 (0.01, 0.07) 0.05 (0.03, 0.10) 0.06 (0.03, 0.12)