Table 1.
The Clinical Characteristics of Enrolled Individuals
| Serum Samples | Tissue Specimens | |||
|---|---|---|---|---|
| Liver Cirrhosis (n=151) | HCs (n=62) | Liver Cirrhosis (n=12) | HCs (n=5) | |
| Age year (IQR) | 53 (18) | 54 (16) | 50 (16) | 53 (14) |
| Gender | ||||
| Male n (%) | 97 (64.23) | 36 (58.06) | 7 (58.33) | 3 (60) |
| Fale n (%) | 54 (35.76) | 26 (41.94) | 5 (41.67) | 2 (40) |
| Aetiology | ||||
| Viral hepatitis | NA | 7 (58.33) | NA | |
| HBV n (%) | 87 (73.73) | |||
| HCV n (%) | 31 (26.27) | |||
| Alcohol n (%) | 15 (9.93) | NA | 2 (16.67) | NA |
| Cholestatic/Autoimmune n (%) | 18 (11.92) | NA | 3 (25) | NA |
| Child-Pugh Classification. | ||||
| A n (%) | 60 (39.73) | NA | 2 (16.66) | NA |
| B n (%) | 46 (30.46) | NA | 5 (41.67) | NA |
| C n (%) | 45 (29.81) | NA | 5 (41.67) | NA |
| Phase | ||||
| Compensated stage n (%) | 48 (31.79) | NA | 4 (33.33) | NA |
| Decompensated stage n (%) | 103 (68.21) | NA | 8 (66.67) | NA |
| APRI score | 2.11 (2.52) | 0.29 (0.11) | 2.1 (2.84) | 0.26 (0.1) |
| AST (U/L) | 63 (89) | 24 (6) | 52 (68.55) | 23 (4.5) |
| PLT | 92 (78) | 204 (76) | 67 (45) | 207 (72) |
Abbreviations: IQR, interquartile range; HCs, healthy controls; APRI, AST to Platelet Ratio Index; NA, not applicable.