Table 3.
Serum Levels of GSDMD, IL-1ß and IL-18 in Patients with Liver Cirrhosis with Complications
| GSDMD | p value | IL-1ß | p value | IL-18 | p value | |
|---|---|---|---|---|---|---|
| LC (Ascites) | ||||||
| - (n=48) | 48.5 (48.47) | p=0.32 | 59.98 (163.58) | p =0.0111 | 99.63 (227.55) | p=0.0104 |
| + (n=16) | 44.29 (31.53) | 159 (268.26) | 294.7 (429.3) | |||
| LC (BEV) | ||||||
| - (n=48) | 48.5 (48.47) | p=0.1299 | 59.98 (163.58) | p =0.0250 | 99.63 (227.55) | p=0.0008 |
| + (n=29) | 38.88 (49.59) | 143.4 (218.81) | 327.5 (425.57) | |||
| LC (SBP) | ||||||
| - (n=48) | 48.5 (48.47) | p=0.0006 | 59.98 (163.58) | p<0.0001 | 99.63 (227.55) | p<0.0001 |
| + (n=42) | 74.13 (47.45) | 282.1 (308.7) | 516.9 (526.6) | |||
| LC (HE) | ||||||
| - (n=48) | 48.5 (48.47) | p=0.0658 | 59.98 (163.58) | p=0.2129 | 99.63 (227.55) | p=0.4357 |
| +(n=16) | 78.88 (58.78) | 80.36 (238.68) | 175.2 (460.28) | |||
| LC (Ascites vs SBP) | ||||||
| Ascites (n=16) | 44.29 (31.53) | p=0.0001 | 159 (268.26) | p=0.09 | 294.7 (429.3) | p=0.18 |
| SBP (n=42) | 74.13 (47.45) | 282.1 (308.7) | 516.9 (526.6) |
Notes: Data are presented as median (interquartile range).
Abbreviations: BEV, bleeding esophageal varices; SBP, spontaneous bacterial peritonitis; HE, hepatic encephalopathy.