Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2021 May 15;41(7):560–575. doi: 10.1002/cac2.12158

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© 2021 The Authors. Cancer Communications published by John Wiley & Sons Australia, Ltd. on behalf of Sun Yat‐sen University Cancer Center

This is an open access article under the terms of the http://creativecommons.org/licenses/by-nc-nd/4.0/ License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non‐commercial and no modifications or adaptations are made.

PMC Copyright notice

ALYREF is up‐regulated in BCa tissues and predicts poor prognosis for BCa patients. (A) Relative expression of ALYREF mRNA in 50 paired BCa tissues and adjacent normal tissues by qRT‐PCR. (B) The typical expression of ALYREF protein in 8 paired BCa tissues (T) and adjacent normal tissues (N) by Western blotting. (C) IHC staining of ALYREF. ALYREF protein is stained in brown and located in both nucleus and cytoplasm. (D) Kaplan‐Meier survival analysis shows that ALYREF up‐regulation predicts poor OS and RFS in BCa patients. The log‐rank test was used to compare differences between the two groups. Abbreviations: ALYREF, Aly/REF export factor; GAPDH, glyceraldehyde‐3‐phosphate dehydrogenase; BCa, bladder cancer; CI, confidence interval; qRT‐PCR, quantitative real‐time polymerase chain reaction; IHC, immunohistochemistry; OS, overall survival; RFS, recurrence‐free survival.