Table 1.
Name | Length (nt) | Function | Example | References |
---|---|---|---|---|
Intergenic | 828 | Control the expression of both near and remote genes | LINC00152, H19, IPW, MEG3 | [35–37] |
Intragenic | — | Attach to promoters and enhancers | RUNXOR | [35, 39] |
Enhancer | — | Specific enhancer–promoter looping, gene expression | IG-DMR eRNAs | [35, 56] |
Antisense | — | Gene regulation, X-inactivation, imprinting, and epigenetic regulation | KCNQ1OT1, AIRN, NESPAS, Ube3a-ATS, ANRIL | [42–44] |
sno-lncRNAs | — | Contribute in the pathogenesis of PWS | — | [42–44] |
circRNAs | Under 100 nt to over 4 kb | Related with disease phenotype | cANRIL | [42–45] |
ciRNAs | — | Gene transcription | — | [42–45] |
lncRNAs: long noncoding RNAs; LINC00152: long intergenic non-protein-coding RNA152; IPW: imprinted gene in the Prader-Willi syndrome region; MEG3: maternally expressed gene 3; RUNXOR: RUNX1 overlapping RNA; IG-DMR: intergenic differentially methylated region; KCNQ1OT1: KCNQ1 opposite strand/antisense transcript 1; AIRN: antisense of insulin-like growth factor-2 receptor RNA noncoding; UBE3A-ATS: UBE3A antisense transcript; ANRIL: antisense noncoding RNA in the INK4 locus.