Table 1.
Demographic and tissue parameters of the postmortem brain samples
CIBERSAM tissues | Patients | Controls | p |
Gender, n | males, 25 | males, 11 | N/A |
Age of death, years. Mean (SD) | 63.84 (16.17) | 71.73 (10.92) | 0.15 |
PMI, hours. Mean (SD) | 8.00 (10.08) | 8.82 (4.94) | 0.80 |
Brain pH. Mean (SD) | 7.12 (0.15) | 7.00 (0.20) | 0.05 |
Cause of death | 6 Respiratory disease, 12 other medical conditions, 7 suicide | 2 Cardiac, 4 Pneumonia, 5 other medical conditions | N/A |
STANLEY RNA | Patients | Controls | p |
Gender, n | males, 23 | males, 25 | N/A |
Age of death, years. Mean (SD) | 41.35 (8.53) | 45.08 (7.82) | 0.12 |
PMI, hours. Mean (SD) | 30.13 (16.09) | 27.88 (12.33) | 0.59 |
Brain pH. Mean (SD) | 6.42 (0.26) | 6.66 (0.24) | 0.0017* |
Cause of death | 11 cardiac disease, 7 other medical conditions, 1 accident, 4 suicide | 23 cardiac, 2 other medical conditions | N/A |
Mean ± standard deviation (SD) are shown for each variable; PMI, postmortem interval; N/A, not applicable; p value obtained when comparing patients and controls using the unpaired t test; * p < 0.05