Table 2.
Demographic and Clinical Characteristics and Laboratory Findings
| Characteristic | Patient 1 | Patient 2 | Patient 3 | Patient 4 | Patient 5 |
|---|---|---|---|---|---|
| Demographic characteristics | |||||
| Age — yr | 41 | 37 | 62 | 79 | 61 |
| Sex | Female | Female | Male | Female | Male |
| Initial findings | |||||
| Medical history | Healthy without rheumatoid arthritis | Healthy without rheumatoid arthritis | Healthy without rheumatoid arthritis | Hypertension, no history of rheumatoid arthritis | Cholecystectomy, chronic gastritis, no history of rheumatoid arthritis |
| Disease severity | Moderate | Mild | Moderate | Severe | Severe |
| Symptoms at disease onset | Fever, cough, fatigue, muscle soreness, headache | Normal | Paroxysmal dry cough | Nausea, poor appetite, occasional vomiting | Fatigue, diarrhea and dyspnea. |
| Imaging features | Abnormal density of the upper lobe, Patchy shadow of left upper lobe of lung | Normal | Patchy changes in both lungs | Multiple infection foci in both lungs | Fibrous proliferative foci in both upper lobes of lung |
| Laboratory findings (Reference range) | |||||
| Total lymphocytes (per mm3) (1100–3200) | 1070 | 1270 | 1000 | 510 | 400 |
| Globulin (g/liter)(20–30) | 26.5 | 24.6 | 27.9 | 30.6 | 28.3 |
| Alanine aminotransferase (U/liter) (7–45) | 30 | 20 | 23 | 15 | 110 |
| Aspartate aminotransferase (U/liter) (13–35) | 27 | 16 | 27 | 34 | 52 |
| C-reactive protein (mg/liter)(0–10) | 12 | 2 | 20.7 | 39.3 | 8.2 |
| Serum amyloid A (mg/liter) (0–10) | 45.95 | 25.39 | 167.56 | 237.58 | 139.83 |
| D-dimer (mg/liter) (0–0.5) | 0.161 | 0.089 | 0.419 | 6.576 | 11.902 |
| Prothrombin time (sec) (9.4–12.5) | 12.8 | 12 | 12.6 | 10.8 | 17 |
| Anti-cardiolipin antibody (0–12) | IgA 0.73 (APL/mL) IgG 1.13 (GPL/mL) IgM 1.82 (MPL/mL) |
IgA 9.88 (APL/mL) IgG 0.52 (GPL/mL) IgM 1.39 (MPL/mL) |
IgA 8.37 (APL/mL) IgG 1.87 (GPL/mL) IgM 0.56 (MPL/mL) |
IgA 1.83 (APL/mL) IgG 36.93 (GPL/mL) IgM 4.36 (MPL/mL) |
IgA 13.62 (APL/mL) IgG 17.78 (GPL/mL) IgM 30.05 (MPL/mL) |
| ANA | Negative | Negative | Negative | Negative | Negative |
| Interleukin-6 (pg/mL)(0–7) | 20.93 | 5.26 | 6.75 | 92.58 | 63.19 |
| Anti-jo-1 (Relative Level) | Feb. 10 7 Mar. 27 88 May 09 76 Jun. 18 65 Jul. 15 63 Jul. 30 55 |
Negative | Negative | Negative | Negative |
Note: The data is the first test result after the patient’s RT-PCR diagnosis except for anti-jo-1.