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. 2021 Jul 12;14:883–896. doi: 10.2147/JAA.S312361

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© 2021 Xue et al.

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Asthma models exhibited bronchial hyperresponsiveness. (A) The baseline is represented by average lung resistance (R_L) value after PBS nebulization (within 2 min) for each mouse. (B) -logPC100 (ACh concentration required to increase R_L by 100% from baseline). (C) Mean percentage increase in R_L with increasing concentrations of ACh. Data are expressed as mean ± SD. In Panel B, **P < 0.01; in Panel C, *P < 0.05, **P < 0.01, compared with the control group.