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. Author manuscript; available in PMC: 2022 Jul 1.
Published in final edited form as: Semin Cancer Biol. 2021 Jan 18;82:120–133. doi: 10.1016/j.semcancer.2020.12.016

Fig. 6. Dynamic relationship between LRIG1 and ERBB family members.

Fig. 6.

(A) In normal prostate tissues, ERBB2 mRNA was expressed at highest levels followed by ERBB3 and EGFR while ERBB4 mRNA was barely detectable, and there was reasonable correlation between the ERBB2 and ERBB3 mRNA levels with LRIG1. Pearson correlation coefficient for linear regression was calculated based on expression data of the 5 genes in 232 normal prostate tissues from the GTEx project, with R and p-value indicated.

(B) In PCa, ERBB3 was expressed at the highest level and there was a significant correlation between ERBB3 mRNA levels with LRIG1. Pearson correlation coefficient for linear regression was calculated based on expression data in 498 PCa samples from TCGA project, with R and p-value indicated.