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. 2021 Jan 18;26(6):2493–2503. doi: 10.1038/s41380-020-00983-1

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© The Author(s) 2021

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Fig. 2 — Nineteen brain states were identified in the resting-state data from 35 patients with SCZ and 35 healthy controls. Three states demonstrated a significantly reduced rate of occurrence in the patients with SCZ compared to the controls (p < 0.001, p < 0.001, p = 0.012, two-tailed t-test, respectively). The maps of these brain states in the healthy controls are displayed in the lower panel. One state demonstrates strong activation in the fronto-parietal control network but deactivation in sensorimotor areas. The second state demonstrates the opposite pattern. The third state involves strong activation in the visual cortex and the insula but deactivation in the default network. See also Supplementary Fig. S2 for the maps of the 19 clusters identified in this dataset and Supplementary Fig. S9 for the results using different cluster numbers (cluster number = 11, 14, 17, 19, 21).