Table 1:

Clinicopathologic characteristics of tumors originally diagnosed as primary pleomorphic adult uterine rhabdomyosarcoma.

Sample ID	Age at diagnosis (y)	FIGO stage	Clinical group	Tumor size (cm)	Histologic subtype	Myogenin	Desmin	Mitosis (#/10 HPF)	Necrosis	Presence epithelial differentiation	AE1/AE3	Clinical Course
uRMS1	90	IV	IV	7.5	pleomorphic	positive	positive	17	Yes	No	No	Surgery, DOD <6 months
uRMS2	74	I	Ia	5.5	pleomorphic	positive	positive	30	Yes	No	No	Surgery, IVRT, length of follow-up <6 months
uRMS3	80	IV	IV	6.2	pleomorphic#	positive	NP	21	Yes	Two minute foci# (0.4 mm each)	Yes#	Surgery, chemotherapy*, DOD <6 months

Staging and clinical group according to Intergroup Rhabdomyosarcoma Study Group (IRSG).^{58, 59} DOD, dead of disease; HPF, high power field; IVRT, intravaginal radiation therapy; NP, not performed; y, years.

^#Following completion of molecular genetic analysis and extensive re-review of the pathology material, this case was favored to be a uterine carcinosarcoma with extensive rhabdomyosarcomatous overgrowth.

^*4 cycles of doxorubicin/cyclophosphamide.