Table 3:

Condition (S-ENG vs CAU) by time interaction in intent to treat analyses

Outcome	Mean Differences (SE)a			Time by condition interaction
	3-weeks	6-weeks	10 weeks
(low) Belonging (INQ)	.82 (.75) z = 1.09, p=.276	−.49 (.75) z = −0.65, p=.514	−.79 (.72) z = −1.09, p=.278	chi2(3) = 4.91, p=0.178b
Perceived burden (INQ)	−.10 (.39) z = −.27, p=.790	−.16 (.39) z = −.40, p=.689	−.20 (.38) z = −.54, p=.591	chi2(3) = 0.32, p=0.957
Depression (QIDS)	−3.16 (.89) z = −3.57, p=.000	−2.21 (.88) z = −2.51, p=.012	−2.47 (.85) z = −2.89, p=.014	chi2(3)= 15.05, p=0.002
Suicide ideation (GSIS)	−.60 (.53) z = −1.13, p=.257	−.27 (.52) z = −.51, p=.609	−.34 (.52) z = −.51,p=511	chi2(3)= 1.31, p=0.726b
Social-emotional quality of life (WHOQOL)3	--	--	5.78 (2.39) z = 2.42, p=.015	chi2(1) = 5.86, p=0.015

Abbreviations:S-ENG, The Social Engage psychotherapy intervention; CAU, care as usual; SE, standard error; INQ, Interpersonal Needs Questionnaire; QIDS, Quick Inventory of Depressive Symptoms; GSIS, Geriatric Suicide Ideation Scale—Screening Form; WHOQOL (World Health Organization Quality of Life Scale).

Notes:All significance tests are two-sided. Models are mixed effects maximum likelihood regressions, with random intercepts at the subject level and fixed effects for time, condition, and condition by time interaction (depicted above). Models with sex and age were run and results were unchanged, thus, more parsimonious models without those covariates are presented.

^aMean differences are represented by ENG=1, CAU=0, such that negative means indicate lower scores for ENG.

^bSignificant effect of time, with scores decreasing for both groups.

³WHOQOL was only administered at baseline and 10-week follow-up.