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. Author manuscript; available in PMC: 2022 Jul 15.
Published in final edited form as: Mol Cell. 2021 Jun 8;81(14):3007–3017.e5. doi: 10.1016/j.molcel.2021.05.014

Figure 3. Partial depletion of RADX causes nascent strand degradation.

Figure 3.

(A-D) Fork protection assays were performed in wild-type, SMARCAL1Δ, HLTFΔ or ZRANB3Δ U2OS cells transfected with the indicated amount of each siRNA. Cells were treated with (B) 100μM Mirin or (D) 25μM B02 where indicated. A one-way ANOVA with Tukey’s multiple comparison test was used to calculate all p values. All experiments were completed at least twice. See also Figure S4.