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. Author manuscript; available in PMC: 2021 Aug 1.
Published in final edited form as: Liver Int. 2021 May 7;41(8):1884–1893. doi: 10.1111/liv.14903

Table 5:

Allelic cluster association between allopurinol cases and controls from BioMe cohort, and between allopurinol cases and disease controls from DILIN.

Analysis subset Clusters Cases AF BioME controls AF p value: Cases vs. BioMe AF DILIN Controls AF P values: Case vs. DILIN AF
African Americans B*35:01,B*53:01 0.43 0.21 0.051 0.25 0.128
B*53:01,B*58:01 0.57 0.17 6.67×10−4 0.20 0.004
All subjects B*35:01,B*53:01 0.32 0.17 0.085 0.10 0.004
B*53:01,B*58:01 0.41 0.12 0.0007 0.04 1.54×10−7

Note: p-values were from Fisher exact test by comparing the allele counts in allopurinol cases to controls from BioMe, and to DILIN cases due to other drugs or herbal (DILIN controls) for all alleles listed in the cluster.