Table 3.
Change in susceptibility of microorganisms to antimicrobials between pre- and postintervention periods for GNB
| Organisms | ||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Acinetobacter spp. | Escherichia coli | Klebsiella spp. | Pseudomonas aeruginosa | |||||||||
| Antimicrobial | Pre | Post | p value | Pre | Post | p value | Pre | Post | p value | Pre | Post | p value |
| Gentamicin | 20% | 35% | 0.01* | 28% | 42% | 0.03* | 26% | 41% | 0.025* | 24% | 37% | 0.04* |
| Piperacillintazobactam | 10% | 18% | 0.1 | 15% | 36% | 0.009* | 14% | 29% | 0.011* | 9% | 25% | 0.003* |
| Imipenem | 22% | 34% | 0.06 | 35% | 47% | 0.08 | 37% | 58% | 0.003* | 27% | 41% | 0.03* |
| Ceftriaxone | 5% | 15% | 0.02* | 11% | 33% | 0.003* | 9% | 37% | 0.001* | 12% | 34% | 0.003* |
| Doxycycline | 30% | 45% | 0.02* | 56% | 65% | 0.19 | 53% | 68% | 0.03* | 42% | 58% | 0.02* |
| Levofloxacin | 33% | 38% | 0.46 | 30% | 46% | 0.02* | 32% | 51% | 0.006* | 36% | 49% | 0.06 |
| Colistin | 76% | 83% | 0.22 | 78% | 92% | 0.008* | 75% | 89% | 0.01* | 68% | 75% | 0.27 |
*
Significance observed in antimicrobial susceptibility, in post-intervention period; p value was calculated using a paired t-test for a row-by-column contingency table with appropriate degrees of freedom. p <0.05 was considered statistically significan