Table 4.
Change in susceptibility of microorganisms to antimicrobials between pre- and postintervention periods for GPC
Organism | ||||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|
S. aureus | CoNS | E. faecalis | E. faecium | |||||||||
Antimicrobial | Pre | Post | p value | Pre | Post | p value | Pre | Post | p value | Pre | Post | p value |
Linezolid | 98% | 99% | 0.6 | 98% | 98% | 1 | 98% | 99% | 0.6 | 97% | 99% | 0.3 |
Doxycycline | 80% | 78% | 0.7 | 83% | 77% | 0.3 | 85% | 82% | 0.6 | 81% | 76% | 0.4 |
Chloramphenicol | 55% | 65% | 0.15 | 50% | 70% | 0.04* | 52% | 70% | 0.09* | 51% | 68% | 0.01* |
Levofloxacin | 20% | 36% | 0.01* | 21% | 35% | 0.03* | 19% | 37% | 0.005* | 19% | 41% | 0.009* |
Clindamycin | 18% | 29% | 0.07* | 19% | 31% | 0.05* | 21% | 38% | 0.009* | 20% | 35% | 0.01* |
Gentamicin | 35% | 53% | 0.01* | 31% | 48% | 0.01* | 33% | 39% | 0.4 | 34% | 37% | 0.7 |
Significant, S. aureus: Staphylococcus aureus, CoNS: Coagulase-negative staphylococci, E. faecalis: Enterococcus faecalis, and E. faecium: Enterococcus faecium; p value was calculated using a paired t-test for a row-by-column contingency table with appropriate degrees of freedom. p <0.05 was considered statistically significant