Table 5B.
Change in antimicrobial consumption for BSI between pre- and post-intervention in GNB causing BSI
| Gram-positive organisms | ||||
|---|---|---|---|---|
| Number of prescribed units | ||||
| Antimicrobial | Dose | Pre-ASP | Post-ASP | p value |
| Doxycycline | 100 mg | 802 | 542 | 0.07 |
| Gentamicin | 40 mg/2 mL | 564 | 421 | 0.05 |
| Levofloxacin | 25 mg/mL | 547 | 443 | 0.008* |
| Piperacillintazobactam | 4.5 g | 761 | 457 | 0.07 |
| Ceftriaxone | 1 g | 670 | 342 | 0.01* |
| Imipenem | 1 g | 944 | 683 | 0.04* |
| Colistin | 3 MIU | 382 | 210 | 0.02* |
*
Significant decline was noted in the prescription of antimicrobials for GNB causing BSI; Data were collected from pharmacy stock regarding purchase or consumption of antibiotics in the two phases; using pharmacy prescription uploaded in HIS, and units of particular antimicrobials prescribed by an intensivist, and its dosage was extracted from the pharmacy portal and evaluated for any changes in antibiotic prescribing habits in ICU.
p value was calculated using the Chi-square test for a row-by-column contingency table with appropriate degrees of freedom. p <0.05 was considered statistically significant