Table 3.
The genotype and allele distribution of the rs11614913 polymorphism in the case and control groups by adjusting deviation from the HWE to the control group
| Genotype | Casen (%) | Controln (%) | OR, 95% CI (Lower-Upper) | P value (χ2, df) | Adjusted OR, 95% CI (Lower-Upper) | Adjusted P value (χ2, df) | Minimum detectable OR |
|---|---|---|---|---|---|---|---|
| RS116 | |||||||
| CC | 74 (38.1) | 100 (35) | Reference group | - | Reference group | - | - |
| CT | 91 (46.9) | 138 (48.2) | 1.09 (0.73 – 1.63) | 0.358 (0.85, 1) | 0.89 (0.60 - 1.33) | 0.772 (0.08 , 1) | 0.57 |
| TT | 29 (15) | 48 (16.8) | 0.76 (0.44 – 1.29) | 0.192 (1.70, 1) | 0.82 (0.47 – 1.42) | 0.591 (0.29 , 1) | 0.46 |
| CT+TT | 120 (61.9) | 186 (65) | 0.98 (0.68 – 1.43) | 0.980 (0.001, 1) | 0.87 (0.60 – 1.27) | 0.477 (0.51 , 1) | 0.58 |
| Alleles | |||||||
| C | 239 (61.6) | 338 (59.09) | Reference group | - | Reference group | - | - |
| T | 149 (38.4) | 234 (40.91) | 0.90 (0.69 – 1.17) | 0.436 (0.61, 1) | 0.90 (0.69 – 1.17) | 0.436 (0.61, 1) | 0.69 |
HWE; Hardy-Weinberg equilibrium, OR; Odd ratio, and CI; Confidence interval.