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. 2021 Jul 18;34(3):125–131. doi: 10.1053/j.semvascsurg.2021.05.005

Table 3.

Summary of key study limitations.

First author Limitations
Ray [21] Inability to test patients who died quickly due to critical illness
Zhao [22] Moderate sample size (n = 2,173), single ethnic group
Li [20] Moderate sample size (n = 2,153), single ethnic group, no covariate adjustment, potential subject overlap with Zhao [22]
Hoiland [17] Very small sample size (n = 95), limited to ICU subpopulation, blood group data missing in 25% of ICU-admitted patients
Leaf [19] Moderate sample size (n = 2,033), blood group data missing in one-third of subjects
Latz [18] Moderate sample size (n = 1,289), lead time bias
Zietz [23] Selection bias for inpatient hospital population due to limited testing
Barnkob [43] ABO data available for only 62% of tested individuals, female sex overrepresented at 71% of negative and 67% of positive subjects
Boudin [45] Moderate sample size (n = 1,279), very high infection rate (76%), subjects not representative of general population (ie, young, healthy)

Abbreviation: ICU = intensive care unit.