Table 3.
Summary of key study limitations.
| First author | Limitations |
|---|---|
| Ray [21] | Inability to test patients who died quickly due to critical illness |
| Zhao [22] | Moderate sample size (n = 2,173), single ethnic group |
| Li [20] | Moderate sample size (n = 2,153), single ethnic group, no covariate adjustment, potential subject overlap with Zhao [22] |
| Hoiland [17] | Very small sample size (n = 95), limited to ICU subpopulation, blood group data missing in 25% of ICU-admitted patients |
| Leaf [19] | Moderate sample size (n = 2,033), blood group data missing in one-third of subjects |
| Latz [18] | Moderate sample size (n = 1,289), lead time bias |
| Zietz [23] | Selection bias for inpatient hospital population due to limited testing |
| Barnkob [43] | ABO data available for only 62% of tested individuals, female sex overrepresented at 71% of negative and 67% of positive subjects |
| Boudin [45] | Moderate sample size (n = 1,279), very high infection rate (76%), subjects not representative of general population (ie, young, healthy) |
Abbreviation: ICU = intensive care unit.